logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name rno-miR-29a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line rat retinal Müller cells; rat retinal Müller cell line rMC-1
Methods qPCR, Western blot, high-performance liquid chromatography (HPLC), transfection, luciferase reporter assay
Expression pattern down-regulated
Functional description Downregulation of microRNA 29a/b, mediated by the sonic hedgehog-glioma-associated oncogene homolog 1 signalling pathway, exacerbated diabetic retinopathy by upregulating Forkhead box protein O4.
PubMed ID 29409329
Year 2018
Title Downregulation of MicroRNA 29a/b exacerbated diabetic retinopathy by impairing the function of Müller cells via Forkhead box protein O4.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.